The Best Photomicrography! What is it?

Celebrating 49 years of images captured by the light microscope.

Story credit: www.nikonsmallworld.com

Nikon’s Small World is regarded as the leading forum for showcasing the beauty and complexity of life as seen through the light microscope. The Photomicrography Competition is open to anyone with an interest in microscopy and photography.  The Nikon Small World Competition first began in 1975 as a means to recognize and applaud the efforts of those involved with photography through the light microscope. Since then, Small World has become a leading showcase for photomicrographers from the widest array of scientific disciplines.

On 17 October 2023, the winners of the 49th annual Nikon Small World Photomicrography Competition were announced. This year’s first place prize was awarded to Hassanain Qambari, assisted by Jayden Dickson of the Lions Eye Institute, for his vivid image of a rodent optic nerve head showing astrocytes (yellow), contractile proteins (red), and retinal vasculature (green). The colorful image provides an important contribution to the study and reversal of diabetic retinopathy, which affects one in five persons with diabetes worldwide.

A rodent optic nerve head showing astrocytes (yellow), contractile proteins (red), and retinal vasculature (green).(Courtesy of Nikon Small World 2023: Hassanain Qambari and Jayden Dickson
A rodent optic nerve head showing astrocytes (yellow), contractile proteins (red), and retinal vasculature (green).(Courtesy of Nikon Small World 2023: Hassanain Qambari and Jayden Dickson

Third place was awarded to Malgorzata Lisowska for her image of breast cancer cells.

Diabetic retinopathy occurs when high blood sugar damages the blood vessels in the tissue at the back of the eye, known as the retina. The damaged blood vessels can swell and leak, which can cause blurry vision or total loss of eyesight. Since 2021, Qambari has devoted his time and research to the early detection and reversal of the disease.

“Current diagnostic criteria and treatment regimens for diabetic retinopathy are limited to the late-stage appearance of the disease, with irreversible damage to retinal microvasculature and function,” said Qambari. “The visual system is a complex and highly specialized organ, with even relatively minor perturbations to the retinal circulation able to cause devastating vision loss. I entered the competition as a way to showcase the complexity of retinal microcirculation.”

Qambari faced some challenges when capturing his image such as locating fine vessels near 110 microns in diameter and establishing a protocol for labeling different cell types. “Over the past 20 years, our research group has refined the technique of isolated ocular perfusion labeling for fine vessels in the eye,” said Qambari. “While the ophthalmic artery in the rodent model presented a technically demanding challenge, we were able to overcome it with persistence and patience.”

The final result educates the public about the universal condition affecting millions and the vital research necessary to further advance care. “The Nikon Small World competition is great, as it showcases amazing work across many disciplines from around the world,” said Qambari. “All the images presented in the competition represent the beauty and artistic side of science which may otherwise get overlooked. Such a competition not only celebrates the participant’s hard work and passion but may also draw and inspire young scientists to pursue a career in STEM. It certainly inspired me.”

Like Qambari, Eric Flem, Senior Manager, CRM and Communications at Nikon Instruments, is passionate about sharing exemplary scientific work and artistic techniques. “The past 49 years of this competition have borne witness to many innovative and pioneering advancements in scientific imaging technology,” said Flem. “I am consistently awed by how these advancements make it possible to create art out of science for the public to enjoy.”

Second place was awarded to Ole Bielfeldt for his image of a matchstick igniting by the friction surface of the box. The image was taken within one eight-thousands of a second and utilized imaging stacking.

Matchstick igniting by the friction surface of the box. Image credit: Nikon Small World, Photographer – Ole Beilfeldt
Matchstick igniting by the friction surface of the box. Image credit: Nikon Small World, Photographer – Ole Beilfeldt

Third place was awarded to Malgorzata Lisowska for her image of breast cancer cells.

Breast cancer cells. Image credit: Nikon SmallWorld, Photographer Malgorzata Lisowska.
Breast cancer cells. Image credit: Nikon SmallWorld, Photographer Malgorzata Lisowska.

In addition to the top three winners, Nikon Small World recognized 83 photos out of thousands of entries from scientists and artists across the globe.

View the top 15 images here on the ABC.net.au site. The images are fascinating.  We’re sure you’ll enjoy them just as much as the UNE Discovery team.

Story credit:  https://www.nikonsmallworld.com/news/rodent-optic-nerve-head-wins-the-49th-annual-nikon-small-world-photo-microscopy-competition

Other source: https://www.abc.net.au/news/2022-10-14/microscopy-photography-nikon-small-world-see-the-photos/101531628